Of course there is a lot of differences between school and college studies. Your successful completion of college studies is only thing that determine your happy future life. To achieve your goal you don't need to strain yourself too much. You just have to give more importance for studies than entertainments, art programs, sports and yoga.
It is very important to choose the course that you love. It would become very difficult for you to complete the course when you choose it for other people's interest. After joining the study course, you should know about the specialty of the course and job opportunities of that particular course. If you gather details about job opportunities, you will get more interest on your selected course.
You should have good habit of noting down important hints and points during lectures. This will help you a lot when you prepare for exam. You can also make use of department libraries and Internet to get more marks in exams.